The Give A [expletive] campaign, a project of Cyndi Lauper's True Colors Fund, released its latest video Thursday during National Runaway Prevention Month to raise awareness about homeless gay, lesbian, bisexual and transgender youth.

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The moving PSA features Oscar winner Susan Sarandon, Tony Award winner Alan Cumming, Rebecca Romijn, Pete Wentz, Eden Riegel and Lauper all urging people to give a [expletive] about this epidemic.

According to the people behind the Give A [expletive] campaign, each year, between 500,000 and 1.6 million young people in the United States are homeless or runaways. Gay, lesbian, bisexual and transgender youth make up an estimated 3% to 5% of the general U.S. population. Yet they make up more than 20%-and possibly up to 40%-of all homeless youth in the country.

Family conflict is the most common cause of all youth homelessness. More than 1 in 4 are actually thrown out of their homes by their parents.